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Metabolic Syndrome
(Metabolic syndrome is
also known as "Syndrome X" or
insulin resistance syndrome)
What is the metabolic syndrome
anyway?
Quite often people
who have either high blood pressure, diabetes, or who are
overweight also
have one or more of the other conditions, although it may have gone
unnoticed.
On their own each
one of these conditions can lead to damage to the blood vessels, but
occurring together they are much more likely to cause harm. When these
conditions occur together people become much more likely to be
affected by heart disease, stroke and other health issues connected
with problems with the blood vessels.
When someone has
such a combination, they're said to have metabolic syndrome. Metabolic
syndrome is also referred to as insulin resistance syndrome
(because one of the features is a very high level of the hormone
insulin in the blood, which the body doesn’t react to or is
'resistant' to) or sometimes syndrome X.
In the Western World
Metabolic syndrome is very common and becoming more so. In the USA,
surveys estimate that as many as one in four adults has metabolic
syndrome. In the UK research suggests that a similar number of people
are affected here. Also it is more common in certain ethnic
groups (Asian and Afro-Caribbean people) and among women who have
polycystic ovary syndrome.
What are the symptoms
-
Increased blood triglyceride (a form of fat) levels
-
Decreased
‘good’ cholesterol levels (HDL cholesterol)
-
Overweight particularly around the abdomen
-
Increased
blood pressure
-
Increased
blood glucose level
If a person has been
diagnosed with any three of the above features they have
metabolic syndrome.
What causes metabolic
syndrome?
Metabolic syndrome
is very complex and doctors have yet to work out exactly what goes on
in the body at the level of the cells and molecules. However, there
seem to be three contributory factors: an inherited genetic tendency,
being overweight and physical inactivity.
It seems some people
are born with a genetic tendency to develop insulin resistance. If
they put on a lot of weight and don’t do enough exercise, they become
insulin resistant and develop the metabolic syndrome.
Is it preventable?
Although much more
research has to be done to work out the relationship between different
factors in metabolic syndrome, and how drug treatments might be used
to help people, there are steps you can take to reduce your risk.
Lifestyle changes
can make a big difference, preventing or delaying the development of
serious disease. Losing weight and getting active are the top
priority. But make sure you get proper advice and support - research
has shown that people who join a weight-loss group, for example, are
more likely to lose weight and keep it off.
In terms of getting
fit, join a gym or find a sport you enjoy. You're more likely to stick
at it if you like what you're doing.
Some preventative
treatments are also available from your GP. It's important to keep
your blood pressure under control, for example. However, some blood
pressure treatments, such as diuretics and beta blockers, can actually
make metabolic syndrome worse.
Check with your
doctor if you're concerned. Drugs to control blood fat and cholesterol
levels, and blood glucose levels, are often needed, too.
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